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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d8da7e8395457250bb8ceb1de86160b0b915b932fab66a92863e76859ed841' 
  AND token = 'qJI4i4GGTDRbLq9ai1/j2nMCOMq+0W+14uZuS6IBCTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}