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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69c1a73d5948cf054c3509e9c3dfcb49ad1c5d5661e3016a115a89639c3828ae' 
  AND token = 'Mk3zXlRUzkV21PCaUiZHyT+3vA1ejAtrpDBIP4pCtug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}