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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2973a2bc47e7c0b2a72acaff7fba23abbac36bb86fa8fea7cdd155b130074bc' 
  AND token = 'QcnpRld5m5uN+AfWYDV7qicvgSHtik8ArNm1RMPM4uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}