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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e853c6bc9d8096c8c1481d002ab2a2eb213bca17b5febdd94cfd292222682dee' 
  AND token = '0yvwhsGMFN1uyg0/TPt3l/xcUMH/nKwd/doCr/dibgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}