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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88144e0d3da0fb186975e594b10be42ffaaadf8163e0837a8a621b896dfb38a9' 
  AND token = 'vHndS7lo2QEXQNDHljGPE0GkbzKkLoC/SYNMChkqvD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}