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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5e228bd0bcd6ef0be39800f22d3e573b259d4afece65af07e7c88384a31433' 
  AND token = 'V9AhFEjA9hvNaXcc25/X+Zz9dMla8Medu6+KGKIbafk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}