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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89f9476269932ec2e8c61c324569fe33f4482bd0586b66001c59daa82582c450' 
  AND token = 'f5ZMy3De6SB14OSrBa3SxvW2wLXwdbcJfAJe8nNyOCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}