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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435a16711a20033936c3acf811a2a3fe12184fc8a47d357a60c4a4c6421da4e2' 
  AND token = 'MAgW0w7Oxpz6Tn5SVSSBJQkaBLgddSNgtw3+5AUkANo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}