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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dd3595195a8219976f6a3815f45daa64e163a09134dd466fdb236d9a1d9292a' 
  AND token = '4vHtgGGsaO5FMx/Iu72ZAH1A2xk4tIFkg+kxcBIW9ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}