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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54560b22f0b76a40cee68603a735aeb6d41e598dfeb3b1a4e921f54cd7f21479' 
  AND token = 'l76rPS69Beai9VMyeTBUGYUUGEVGRk9bTs6OoLT3SmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}