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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc22c73d1ac4907044a3bbd803cf5a828a2be1f614c009f79df6a6619221c4b' 
  AND token = 'TDzMZRDO8naWiFZRtgGSVClerdK87a4C1dm2SfO8AAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}