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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e10d25801a9e52e652d7d9a22410bb28205b9ead29abab9e3e5b4d08a08061' 
  AND token = 'x9ZlDf0LtRGJG6wQ/bLRQVWp/Qsk8mjMtMyez+9PZ9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}