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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246dca7cbbb9427fa8e610271b3b8e461c89b134aaace4a46d5a0dad610e7044' 
  AND token = 'w3xcfhkWCen98VwpSmyEf+yyaBrBHM8gT2ppngRyMR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}