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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72fd8879911a45212d1ebb6e7d838a7b9af8eb509a92d24e66344783205ffc45' 
  AND token = 'J6uJ2TVlvIKu1DEyvWL49uxDKy3S1Fur0FIHhkk7Ric=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}