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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f88bbbbad26a68d4817ecbf4ec5c4bf43db5722911a0eaeb4313c9e6ed010f7' 
  AND token = 'qITcNiNtzXC5CWlGm+2m7vtR5HFKHNTJQ5MC89LYGPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}