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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4ce253fa693b117643b50dc985ea3e6875af5f3c6565c9de7266c397971a86d' 
  AND token = 'EaAPOsxYhOrAu4IoSeAFkIUL+88fPXYJuBBzsHEO5HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}