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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a55383ed0326fed1a073fca03d62b43070b111d27fa024dae8d6bf456a37f8e' 
  AND token = '1D0c+IzMv6DD6pZIG4LDEAI+IzE1jeLIe1hllRmNOM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}