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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d088099b5fcff20fbf8132a106f1bdb29d9d46133191f075c57d1597a36cb15' 
  AND token = 'P3D8NwfXxb/MefWcGsuAj7y8IrQgvkbc8NmhibOT3kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}