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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3e07f631d7fd97751736f75457fe08cdc8f8c213818499122aa8f82c809d721' 
  AND token = 'T05wfrRJl5T3yxUO8V2sJb5FE0Ugm81ckHmqBwI+rO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}