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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a85b67bf392fb7a495c3bf1bc0092d70cab8630d68e145686454b3c47949b11' 
  AND token = 'imw5sEWicWJpyzj8xRoP3yLTdtpNMUMEN6mvhhW1c9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}