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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7779c16a82709bc5c934201a0c72f3c39581b11a9a8ea4973f798422face820c' 
  AND token = '0ir4faClOIqK4CG6wInjqhPoPthQBT+T/7pIz5XK2eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}