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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d6d5657a75d881a7b6f5cbc9eb9530d576f479bed0adb6eea6244efc14608a' 
  AND token = 'msoqZNl9aRyqh8F2v808YkNpZQXrfWkd1jzXyhY57d4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}