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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '120f3108c33eda8ccef59dce50a440bcc83b493ca180d4d45f8c260715e77324' 
  AND token = 'Rw7fuEdE7GiEHiES21xbHJT8R3PjPx/gQ0J9TUoDnTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}