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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7918a71515b5712d901686844d6c8ba1ba15400ce0f3c478fed46678404bbe0a' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}