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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa73faa64e0e2f86fbca154868742e95c3366cbecb749cdeed1545ab2cb6d1e5' 
  AND token = '2oKZUBORpsdT9rN5b4Lvlj8xhVBCoNgX2fg46kZ1WfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}