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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '528a5653343296959086a56337482bf9f04a111d6eb13b3bb82b885d0914b260' 
  AND token = '2HNWDO4Rc9640TmkXGY+sPCnB6REn9U4flijgThszig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}