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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d65c167753f9c8dc95e028f6c0146d41a1c8b6f0c1f2bbdd49a25628161cf0' 
  AND token = 'gwZfwCYv6cQmIIhHugJa5LJfdtggWWqjfazcQHHfyz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}