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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48e9a56b4b3d4200ad37af45b0f5154f98b7d83eb096134222d2c680b8e6f40' 
  AND token = 'XFxbpIgjZKAZYguqc6O2wW3Tg0EAIw39w0xYx/IEhJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}