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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b13149bd3610df937ebbf33eb8df4eb6d8a81bfedaba64c2c4b9e8da5f367e21' 
  AND token = 'ZutN9KOAtZnPnh1r8i+axUyELhqC05T5eBFqQT3/KBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}