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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07e750260443f0cbcd310e1f847aefbd8a5e1ea81c92a840466319345ace0654' 
  AND token = 'FrDXxGZ2A9KtjZcwl1fUg6cpwG0f/hqzQ3jbq29Cf4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}