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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b936da492d6f9a4b0eba2e6def5c1653913e0c8ab21768fa3b055e4116c8c5a' 
  AND token = 'jbn7rJzMswJ+bl58tH//1+gxP/wlt+f+IZwlD2HolR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}