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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92e427fbd725433bb7f7376ec321356bb738df230a32e1f2d74c66dc801826d1' 
  AND token = 'lXUUD8vwxS7bi4URUjkv/X+ijGpYHXhJuQSF9eAystE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}