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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628b75b2fe700b9faffe5b0d7005e0eb31ed6f77274996ecb0f91d3ac9c71789' 
  AND token = 'M2pTBrp8laODfQEee5GHSFr+22KaLQ9ZacwSH0aqihE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}