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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5abf42c74bf7a58a44f114a6dec835ceaa561e2f6c21c4fa3aca39a59fdf010b' 
  AND token = '5BmM/Rt8iH4MWbFu5fCzpGMUSPhMF1/SZA+lhhOAAj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}