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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e80828dc3ca293bca48073bfc1f768d3df6acd91ad0192c04c9c80c38a3c82' 
  AND token = 'QhpJFNOBLtP5/XgSAdRsXkpbQYjax1AKNpB7mlwVjN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}