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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '365e7833defaf7ac0676e47a73493bdd6fbc46409d0e2fd2b87db1987d1e43bf' 
  AND token = 'Pk2T7BrrSSpHvsu0PxwyAZ798ObrCCxP5vA6kK+XzAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}