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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0a0ae8d284694d749c84e821ac38b3e38f3cb52f644617fd5d4fc81309e1fa' 
  AND token = 'IggG7d4Aw4b0Owab+lPb1UWdprDJ0FCrGYnisx2a7mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}