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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe8543b5bfe3c2a330f3e4eb3e01f01683496125ce4d5f081eadbbe0b6c3d14' 
  AND token = 'WhIYmR9M17tZrn/axVzM8408D+cXkimwBPGyBMtZNBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}