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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2ca935ec53a5d633ea70875c89cf4f29506a659fc2bba2fac587795ed2e2362' 
  AND token = 'S+1cH0RuK5qz58TR4m3HC4rLRPLV9JUi+GX7m1vMWRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}