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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1ce89951874dd3edabce47556e7077dbbd9f55fc1d9ff4795b266fb72b9b37' 
  AND token = 'ckiU+6a8iJUByR6xnrYnYSL8swIOqYt5REFFfSC0hVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}