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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d52c43a470c768ee2154deeaf389cb095d5db560da7bf9a7f3ac41ac7a8d1d' 
  AND token = 'ek//k7uZ//c2gcXHgNm9PUqeVp2hwUasJy+qDv87Rwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}