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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9223187ab8c8ae7bece0d5eb858763f07863b12f0b39e6b0c566f990506e83c8' 
  AND token = 'MVcnsqZFu1Wko1UdQCCyy+HyuBErGX2rQS/SFrqtdB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}