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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743a7770c853257241ace70711ac36409812316fd52587e4578927d90f7e3052' 
  AND token = 'R+gRW1Jn+cxPnebAA0yIcGjF9XjaX6ZhuiYVB30rQtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}