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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b43b643f51aaeb1792e8efc997407d91e4729e39cef30dd72bc59a4d56794cd0' 
  AND token = '5b1r4DyMUB1TPuraHki21N7mfKZj2IZjN9SgtPiKqQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}