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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c85b8eaf9328f83065bff7717ba00f78c0ca19acd6159a6171d46c9f20aa6e' 
  AND token = 'uOhPVONrUCS8ymCuhS80XnZOccILYmxPHCrqHZ/9Hwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}