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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522e3f5ecd08a267a6f69d7d7e6bb97dbc85f2dc2b597c8d594db65956b0474b' 
  AND token = 'vpQanV/f6f8dOkKrn6bXEEg8gHtrPlyEm2PWxiNSY3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}