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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cdac804d3161dc760fdf84e1b8276e9c17b8169dbb2fd8b91afc072ff4b011e' 
  AND token = 'ooO6p/ZpoZ/GFOuRs8vFPqoBu+hnl0v6tysagqJFaCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}