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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e28290b24b735424d4ede9c64746348ba9411989928992a40c4cb7f4dcb87a' 
  AND token = 'u+21ICvQY/n2VPHIsSb0CcCfx95QNMMbgrjqra1Z6sY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}