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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df665a98009b54aeba96f04b68440dab2a50b2d6359105fc7d180e3f8af844f' 
  AND token = '2MQk9vTRwy/q84cSZgRAGxFjT4osLLN9UZOWUb/Gjwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}