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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dfc121017ff3d0ca63138aa88f10696d2e2a65fe3c26d6ac7cd576d626bb497' 
  AND token = 'CetjbUz9v9TTsfprdg5iV3U1EdKSlR13ShCyzr2gXhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}